Actually, this shoulnd't be happening any more with the latest plugin releases (i.e. from 0.5 on), whatever your Windows drive is.
Can you be more specific about your configuration and the error you get?
Also, can you run GIMP from the command line doing the following?
Go to Start menu -> Exec…, then type cmd and press enter. In the console, write:
cd %ProgramFiles%\GIMP-2.0\bin
gimp-2.6 -c --verbose > "%HOMEDRIVE%%HOMEPATH%\Desktop\out.txt" 2>&1
then do whatever you need to do to make the error appear (possibly nothing) and close GIMP. A file named
out.txt should have appeared on your desktop. Either upload it somewhere or copy and paste its content here. Thanks.
(Note: I assumed you're using GIMP 2.6)